Investigational Glaucoma Drainage Implant
Exploring the potential of alternative surgical treatments for the leading cause of blindness worldwide.
Developing an investigational glaucoma drainage device intended for use when surgical intervention is recommended.
- Will utilize a durable filtering technology with a stable biopermeable interface, intended for treating moderate-to-severe glaucoma
- Developed in collaboration with ophthalmologists and glaucoma specialists
- Feasibility studies and subject recruitment in planning stages
Tackling the leading cause of blindness
Pressure build-up in the eye from glaucoma, if left untreated, inevitably leads to optic nerve damage and vision loss.
- The most common cause of irreversible blindness, affecting 2.7 million people in the U.S. alone1
- Well managed in early stages through daily topical drug therapy but patient compliance with self-administered eye drop medication regimens is low
- Surgical intervention has high risk and failure rates (in some cases exceeding 30% after five years2), and is used only after all lower-risk, less-effective options have been exhausted
Seeking a new solution for pressure relief
Investigating the possible patient benefits of using novel materials and designs may have the potential to provide an alternative to incisional procedures for moderate-to-severe glaucoma.
- The implant uses a unique fluid-permeable reservoir, providing stress relief and stable filtering
- Gore material may facilitate biointegration without use of antifibrotics or other medications indicated for reduction of tissue scarring
- Bicket AK, Szeto J, Roeber P, et al. A novel bilayered expanded polytetrafluoroethylene glaucoma implant creates a permeable thin capsule independent of aqueous humor exposure. Bioengineering & Translational Medicine 2020;6(1):e10179.
- Bicket AK, Pitha I. Overcoming bleb encapsulation with biomaterials. Glaucoma Today 2022;2:22-25.